Publications related to Genetics of Hearing | Maryland Cochlear Implant Center of Excellence l Hearing and Speech Sciences Department l University of Maryland

Mitra S, Drake V, Margulies Z, Milon B, Song Y, Depireux D and Hertzano R (2017) The impact of sex on the response to noise and otoprotective therapies against acoustic injury in mice; Association for Research in Otolaryngology, Baltimore, MD, USA
Song Y, Milon B, Ott S, Zhao X, Sadzewicz L, Mahurkar A and Hertzano R (2017) RiboTag-Sew: a comparative analysis of library prep approaches for sequencing low input translatome samples; Association for Research in Otolaryngology, Baltimore, MD, USA.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith Wand Hertzano R. (2015) RFX transcription factors are essential for hearing in mice. Nat Commun, 6:8549.
Hertzano R and Elkon R. (2012) High throughput gene expression analysis of the inner ear. Hear Res. 288:77-88
Hertzano R, Elkon R, Kurima K, Morrisson A, Chan SL, Sallin M, Biedlingmaier A, Darling D, Griffith AJ, Eisenman DJ, Strome SE. Cell type-specific transcriptome analysis reveals a major role for Zeb1 and miR-200b in mouse inner ear morphogenesis. PLoS Genet. 2011 Sep;7(9):e1002309.
Kurima K, Hertzano R, Gavrilova O, Monahan K, Shpargel KB, Nadaraja G, Kawashima Y, Lee KY, Ito T, Higashi Y, Eisenman DJ, Strome SE, Griffith AJ. A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler mice. PLoS Genet. 2011 Sep;7(9):e1002307
Choi BY, Stewart AK, Madeo AC, Pryor SP, Lenhard S, Kittles R, Eisenman D, Kim HJ, Niparko J, Thomsen J, Amos KS, Nance WE, King KA, Zalewski CK, Brewer CC, Shawker T, Reynolds JC, Butman JA, Karniski LP, Alper SA, Griffith AJ. (2009). Hypo-functional SLC26A4 variants associated with nonsyndromic hearing loss and enlargement of the vestibular aqueduct: genotype-phenotype correlation or coincidental polymorphism? Human Mutation, 30: 599-608.
Choi BY, Stewart AK, Madeo AC, Pryor SP, Lenhard S, Kittles R, Eisenman D, Kim HJ, Niparko J, Thomsen J, Amos KS, Nance WE, King KA, Zalewski CK, Brewer CC, Shawker T, Reynolds JC, Butman JA, Karniski LP, Alper SA, Griffith AJ. Hypo-functionalSLC26A4 variants associated with nonsyndromic hearing loss and enlargement of the vestibular aqueduct: genotype-phenotype correlation or coincidental polymorphism? Human Mutation 2009; 30: 599-608
King KA., Choi BY, Zalewski C, Madeo AC, Manichaikul A, Pryor SP, Ferruggiaro A, Eisenman D, Kim HJ, Niparko J, Thomsen J, Butman JA, Griffith AJ, Brewer CC. SLC26A4 genotype, but not cochlear radiologic structure, is correlated with hearing loss in earswith an enlarged vestibular aqueduct (EVA). Laryngoscope 2009; 120: 384-389
King KA., Choi BY, Zalewski C, Madeo AC, Manichaikul A, Pryor SP, Ferruggiaro A, Eisenman D, Kim HJ, Niparko J, Thomsen J, Butman JA, Griffith AJ, Brewer CC. (2009). SLC26A4 genotype, but not cochlear radiologic structure, is correlated with hearing loss in ears with an enlarged vestibular aqueduct (EVA). Laryngoscope,120: 384-389.
Hertzano R, Shalit E, Rzadzinska AK, Dror AA, Song L, Ron U, Tan JT, Starovolsky Shitrit A, Fuchs A, Hasson T, Ben-Tal N, Sweeney HL, Hrabe de Angelis M, Steel KP and Avraham KB. (2008) A Myo6 mutation destroys coordination between the myosin heads,
Hertzano R, Shalit E, Rzadzinska AK, Dror AA, Song L, Ron U, Tan JT, Starovolsky Shitrit A, Fuchs A, Hasson T, Ben-Tal N, Sweeney HL, Hrabe de Angelis M, Steel KP and Avraham KB. (2008) A Myo6 mutation destroys coordination between the myosin heads, re
Hertzano R, Dror AA, Montcouquiol M, Ahmed Z, Ellsworth B, Camper S, Friedman TB, Kelley MW and Avraham KB. (2007) Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory, but not in the vestibular system. Eur J Neurosci. 25:999-10
Fiolka K, Hertzano R, Zeng H, Hermesh O, Avraham KB, Dührsen U and Möröy T. (2006) Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Reports. 7:326-33.
Clough RL, Sud R, Davis-Silberman N, Hertzano R, Avraham KB, Holley M, Dawson SJ. (2004) Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity. Biochem Biophys Res Commun. 5;324:372-81.
Hertzano R, Montcouquiol M, Rashi-Elkeles S, Elkon R, Yücel R, Frankel WN, Rechavi G, Möröy T, Friedman TB, Kelley MW and Avraham KB. (2004) Transcription profiling of inner ears from Pou4f3ddl/ddl identifies Gfi1 as a target of the Pou4f3 deafness gene.
Rhodes CR, Hertzano R, Fuchs H, Bell RE, Hrabé de Angelis M, Steel KP, Avraham KB. (2004) A Myo7a mutation co-segregates with stereocilia defects and low frequency hearing impairment. Mamm Genome. 15:686-97
Rhodes CR, Hertzano R, Fuchs H, Bell RE, Hrabé de Angelis M, Steel KP, Avraham KB. (2004) A Myo7a mutation co-segregates with stereocilia defects and low frequency hearing impairment. Mamm Genome. 15:686-97.